Information: Fexofenadine patent
The present invention provides an immediate release oral pharmaceutical composition comprising a therapeutically effective amount of fexofenadine or its. Fexofenadine undergoes negligible metabolism (hepatic or non-hepatic), as it was the only major compound identified in urine and faeces of animals and man. The plasma concentration profiles of fexofenadine follow a bi-exponential decline with a terminal elimination half-life ranging from 11 to 15 hours after multiple dosing.
The fexofenadine compositions of the invention exhibit improved bioavailability as. Fexofenadine hydrochloride is a white to off-white crystalline powder. It is freely soluble in methanol and ethanol, slightly soluble in chloroform and water, and insoluble in hexane. Fexofenadine hydrochloride is a racemate and exists as a zwitterion in aqueous media at physiological ph.
Fexofenadine is the major active metabolite of terfenadine and is administered as. Fexofenadine, sold under the trade name allegra & fx 24 among others is an antihistamine. Want to know whether the new generic cialis (tadalafil) is worth the hype? Find out more about how they compare.
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